Neurochirurgie
Recherche et Enseignement

Recherche

Le service de Neurochirurgie est affilié à l’équipe de Recherche INSERM Intégration Centrale de la Douleur, qui étudie les mécanismes des douleurs chroniques et explore des traitements novateurs au service des patients qui souffrent.

 

En partenariat avec d’autres CHU et établissements publics à caractère scientifique et technologique (EPST), il participe à plusieurs projets de recherche collaboratifs sur les tumeurs cérébrales, les douleurs chroniques réfractaires, l’organisation du langage dans le cerveau humain, ou encore la chirurgie du rachis (prothèses discales).

 
Enseignement

En ce qui concerne ses missions pédagogiques, le service de Neurochirurgie est rattaché à l’Université Jean Monnet et la Faculté de médecine Jacques Lisfranc de Saint-Etienne. Dans ce cadre, il dispense des enseignements aux étudiants en médecine et aux médecins en formation, mais aussi dans d’autres champs professionnels de la santé (écoles de masso-kinésithérapie, instituts de soins infirmiers).

 

Publications internationales

Depuis 2011, plus de 40 articles ont été publiés dans des revues scientifiques internationales.

 

• Robot-guided neuronavigated repetitive Transcranial Magnetic Stimulation (rTMS) in centram neuropathic pain. An update of long-term follow-up. Archives of Physical Medicien and Rehabilitation 2018

 

• Inter-individual variations and hemispheric asymmetries in structural connectivity patterns of the inferior fronto-occipital fascicle : a diffusion tensor imaging tractography study. Surgical and Radiologic Anatomy 2018

 

• Added value of multiple versus unique sessions of rTMS in predicting motor cortex stimulation efficacy for refractory neuropathic pain. Journal of Neurosurgery 2018

 

• Hearing eyelid movements on the side of a superior semicircular canal dehiscence. European Archives of Oto Rhino Laryngology 2017

 

• An 11-year-old boy with a leptomeningeal tumor. Brain Pathology 2017

 

• Easy method to make the neuronavigated targeting of DLPFC accurate and routinely accessible for rTMS. Clinical Neurophysiology 2017

 

• Dumont B, Forest F, Dal Col P, Karpathiou G, Stephan JL, Vassal F, Péoc’h M. PD1 and PD-L1 in ependymoma might not be therapeutic targets. Clin Neuropathol

 

• Spinal T-cell-rich B-cell lymphoma. Clinical Neuropathology 2017

 

• Vagoglossopharyngeal neuralgia revealed through predominant digestive vagal manifestations. Case report and literature review. Neurochirurgie 2016

 

• CSF lumbar drainage: A safe surgical option in refractory intracranial hypertension associated with acute posttraumatic external hydrocephalus. Acta Neurochirurgica Suppl 2016

 

• Combined DTI tractography and fMRI study of the language connectome in healthy volunteers: extensive mapping of white matter fascicles and cortical activations. PLoS One 2016

 

• Boutet C, Vassal F, Celle S, Schneider F, Barthelemy JC, Bernard L, Barral FG, Roche F. Incidental findings on brain magnetic resonance imaging in the elderly: the PROOF study. Brain Imaging and Behavior 2016

 

• Robot-guided neuronavigated rTMS as an alternative therapy for central (neuropathic) pain: clinical experience and long-term follow-up. European Journal of Pain 2016

 

• Presurgical assessment of the sensorimotor cortex using resting-state fMRI. American Journal of Neuroradiology 2015

 

• Ex vivo confocal microscopy imaging to identify tumor tissue on freshly removed brain sample. Journal of Neurooncology 2015

 

• Cerebral relapsing meningioma : a surgical series with lack of reliability of standard parameters establishing prognosis. Anticancer Research 2015

 

• BRAF V600 point mutation is not present in relapsing meningioma. Clinical Neuropathology 2015

 

• New insights into the functional significance of the frontal aslant tract. An anatomofunctional study using intraoperative electrical stimulation combined with diffusion tensor imaging-based fibre tracking. British Journal of Neurosurgery 2014

 

• Modulation of laser-evoked potentials and pain perception by transcutaneous electrical nerve stimulation (TENS) : a placebo-controlled study in healthy volunteers. Clinical Neurophysiology 2013

 

• Intraoperative use of diffusion tensor imaging-based tractography for resection of gliomas located near the pyramidal tract: comparison with subcortical stimulation mapping and contribution to surgical outcomes. British Journal of Neurosurgery 2013

 

• Intraoperative visualization of language fascicles by diffusion tensor imaging-based tractography in glioma surgery. Acta Neurochirurgica (Wien) 2013

 

• Improve dexterity after chronic electrical stimulation of the motor cortex for central pain. A special relevance for thalamic syndrome. Stereotactic Functional Neurosurgery 2012

 

• Direct stereotactic targeting of the ventrointermediate nucleus of the thalamus based on anatomic 1.5-Tesla MRI mapping with a white matter attenuated inversion recovery (WAIR) sequence. Brain Stimulation 2012

 

• En bloc resection of a multilevel cervical chordoma with C-2 involvement : case report with 2-year follow-up and description of operative technique. British Journal of Neurosurgery 2012

 

• Solitary fibrous tumours of the central nervous system: report of five cases with unusual clinicopathological and outcome patterns. Acta Neurochirurgica (Wien) 2011